House S2E02

I like House, but I have to ask the question, has there ever been a tv show so reliant on one actor and his or her performance? I haven't seen any in recent years. Granted my knowledge base of classic tv shows is rather small, however, nothing dependent on one performance comes to mind. Some people would argue that 24 is that way, that no Jack Bauer = no 24. Others (including Kiefer Sutherland himself) believe that the real time format is the true star. 24 would change significantly without Kiefer, but it would still function as a cool tv show (that's not to say I think it would be near as good as it is now, because it wouldn't, his mannerisms, sayings, and facial expressions add so much to the show that it would be impossible to replace him...just as it is impossible to replace David Palmer, now can someone give me a good reason for killing Palmer off? Didn't think so.). Without Hugh Laurie, House would fall flat on its face. Does anyone really care about House's medical team or his boss? Robert Sean Leonard is great as Wilson but would the show lose anything significant if he or anyone else left? No. You tune in each week to see House berating his patients, uttering insanely untactful analyses, and making fun of just about every other character. Without the main character, the show would fail. I guess that's why they named it House M.D. If you take the principal antagonist out of the picture you have to change the title. And then it really would be a different tv show.